Some psychologists suggest that the traits attributed to Indigo Children can overlap with recognized psychological profiles, particularly those associated with giftedness, high sensitivity, or conditions like ADHD.

Many characteristics associated with Indigo Children—such as being easily bored by routine tasks, difficulty with authority, strong emotional reactions, high energy levels, and a need for creative expression—bear a striking resemblance to traits observed in gifted children or those diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD). For instance, a gifted child might challenge teachers due to boredom or a desire for deeper understanding, not spiritual defiance. Similarly, a child with ADHD might struggle with traditional classroom settings, appear impulsive, or have intense emotional responses. Psychologists are concerned that parents, by identifying their child as 'Indigo,' might neglect proper diagnoses and appropriate interventions for legitimate developmental or psychological conditions, potentially hindering the child's true needs and development.